Glucose-insulin dynamics: a grey-box analogy

Regulating plasma glucose levels for both type I and II diabetic patients is a challenging task. Understanding the effects of meals taken, physical exercises stress will contribute significantly to overall management levels. This paper provides an extension Bergman minimal model represent 12-compartmental models associated with interactions within semi-closed loop system using stochastic differential equations (SDE). The mathematical modelling constructed following grey-box analogy as applied on identifiable patient. Obtained results from study demonstrate predictive capability be good its sensitivity enhanced increased dataset.